Specificity of one-base mismatch detection with MagiProbe
نویسندگان
چکیده
منابع مشابه
Label-free visual detection of nucleic acids in biological samples with single-base mismatch detection capability.
We have combined an allosteric molecular beacon for target recognition and guanine-rich DNAzyme for signal amplification to develop a new platform for visual detection of nucleic acids with single-base mismatch detection capability. The fully DNA-structured platform can undergo color change in response to target DNA/RNA, which enables sensitive and selective visual detection in biological samples.
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Single-base mismatch discrimination by T7 exonuclease with target cyclic amplification detection.
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ژورنال
عنوان ژورنال: Nucleic Acids Symposium Series
سال: 2003
ISSN: 0261-3166,1746-8272
DOI: 10.1093/nass/3.1.165